About TCM-Blast

Traditional Chinese Medicine Basic Local Alignment Search Tool (TCM-Blast) is a web interface for traditional Chinese medicine protein and DNA sequence similarity searches. It contains about the size of 40G traditional Chinese medicines¡¯ genome data, including protein and DNA sequence for 36 traditional Chinese medicines with high medical value.The development of a publicly accessible traditional Chinese medicine genome alignment database hosted on the TCM-Blast website ¨C http://viroblast.pungentdb.org.cn/viroblast/viroblast.php- expands to query multiple sequence databases to obtain TCM genome data, and provides friendly output for easy analysis and browsing of BLAST results.

The user can directly enter the query sequence by pasting the query sequence into the query box or uploading the sequence as a FASTA file from a local file. TCM-Blast provides multiple TCM sequence databases. Users can then select special TCMs¡¯ genome database to run different programs (blastn, blastp, blastx, tblastn, tblastx). TCM-Blast consists of five general BLAST form types[45-48] for TCM genome data: blastn: search TCMs nucleotide databases using a nucleotide query. blastp: search TCMs protein databases using a protein query. blastx: search TCMs protein databases using a translated nucleotide query tblastn: search TCMs translated nucleotide databases using a protein query. tblastx: search TCMs translated nucleotide databases using a translated nucleotide query

With the common features of other BLAST tools, the ViroBLAST provides features like:

  1. Blast multiple query sequences at a time via copy-paste sequences or upload sequence fasta file.
  2. Provide email option to receive the result via email.
  3. Blast against user's own sequence data set besides the public databases on ViroBLAST.
  4. Blast against multiple sequence databases simultaneously.
  5. Summarize results via tabular output and allows further analysis.
  6. Download sequences in databases that match user's query sequences.

Please cite the following paper if you use ViroBLAST:

Chen Z, Li J, Hou N, et al. TCM-Blast for traditional Chinese medicine genome alignment with integrated resources[J]. BMC plant biology, 2021, 21(1): 1-7.